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Associate Scientist - Recombinant Protein Development

Full time San Diego, California Req ID JR-043834
Scientists wearing lab coats

BioLegend | About Us

At BioLegend, we are committed to providing researchers with the most comprehensive and cutting-edge high-quality reagents for life science research. Being part of Revvity, a global provider of health science solutions, technologies, expertise and services for life sciences and diagnostics, allows us to extend the mission of enabling our customers to do legendary discovery. Join us and make a difference!

Job Summary

BioLegend is looking for an Associate Scientist to join the Recombinant Protein team. This position is responsible for developing functional protein products using cutting-edge protein expression and purification technologies. The individual will contribute to business revenue by transforming scientific knowledge into high-quality, sellable products.

The candidate should demonstrate a strong ability to self-start and adapt to the company’s quality system. Duties include designing and implementing gene-to-protein workflows to produce high-quality recombinant proteins for use as research reagents in a fast-paced environment. The individual will develop and optimize protein expression, purification, and characterization processes across both prokaryotic and eukaryotic expression platforms. The candidate should possess excellent critical thinking and technical skills, along with sufficient troubleshooting experience to develop products efficiently while ensuring quality and safety. The individual will also participate in initiating sustainability efforts for existing designs based on market demand.

This position offers an excellent opportunity for technology exploration, scientific knowledge expansion, leadership development, and career growth within a leading biotechnology company.

The individual will perform laboratory-based protein processing, including cell lysis, refolding, and purification using various preparative chromatography methods, to develop final product formulations. They will actively collaborate with multidisciplinary teams to ensure the on-time delivery of internal and external custom orders and projects within the organization.

Essential Functions

Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

  • Familiar with recombinant protein product expression platforms of various protein families such as cytokines, growth factors, enzymes, ligand receptors, and recombinant immunogens from different research areas such as carcinogenesis, immunology, neuroscience,etc.  
  • Implementbacterial protein expression cultureand developand run protein purification schemes using various chromatography methods on various platforms (i.e.,AKTA FPLC, HPLC).
  • Follow GDP (GoodDocumentPractices)on processing records and conducttechnical transfer under ISO9001:2008/ISO13485:2016 standards.
  • Participate in product design and developmental stage review. Provide quality records to ensure traceability and risk control for productreleasing.
  • Own assigned product family in new product development andis responsible fordriving projects to their completion. 
  • Supporttroubleshootingand optimizationonprotein expression, homogeneity, and stability of developing and released products.
  • Work with the team and QA toexecute andvalidatedifferent proteinprocesses,equipmentandchemistry protocols.
  • Support tofacilitateManufacturing Group for purification/QC workflow development and SOP optimizing/ troubleshooting in various production stages,including expression constructs, culture systems, purification schemes, formulation,and stability issues.
  • Establish, coordinate,and communicate project timelines and deliverables withinternal,and external teamto provide weekly, monthly, and quarterly reports.
  • Responsiblefor personnel training, goalsettingand performance management.
  • Maintain a current knowledge of protein chemistry, synthetic biology, and scientific literature. 
  • Other project responsibilities may berequired.

    MinimumQualifications–Education and Experience

    • B.S.degreewith minimum 6years’ experiencein Biotechnology industry
    • M.S.degreewith minimum 3years’ experiencein Biotechnology industry
    • 3+ years of hands-on experience with protein purification via various chromatographymethods.

    Preferred Qualifications– Education and Experience

    • PhD degreein Biotechnology industry withdemonstratedquality system knowledge including ISO 13485. 
    • Experience in protein product production including protein expression andpurificationproteins 
    • Extensive experience in protein or antibody purification and modification.
    • Extensive experience in process optimization for production scale up.

    Work Environment& Physical Demands

    Lab

    While performing the duties of this job, the employeeregularly worksin a laboratory environmentwith occasional data entry on a computer.Occasional exposure to a warehouse environment.

    The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

    While performing the duties of this job, the employeeis regularly required touse hands and fingers to handle, feel, oroperateobjects,toolsor controls, and reach with hands and arms. The employee isfrequentlyrequired to stand,talkand hear. 

    The base salary range for this full-time position is$90,000 - 100,000. This range reflects the minimum and maximum target for a new hire in this position. The base pay actually offered to the successful candidate will take into account internal equity, work location, and additional factors, including job-related skills, experience, and relevant education or training. Your recruiter can share more about the specific salary range for your preferred location during the hiring process. 

    Please note that base pay is only one part of our total compensation package and is determined within a range. This range allows for the successful candidate to have an opportunity to progress within the position and develop at our company. This base pay range does not take into account bonuses, equity, or other benefits which may be applicable and are dependent on the level and position offered.


    What do we offer?

    We provide competitive and comprehensive benefits to our employees. Below are some highlights of our benefits:

    • Medical, Dental, and Vision Insurance Options
    • Life and Disability Insurance
    • Paid Time-Off
    • Parental Benefits
    • Compassionate Care Leave
    • 401k with Company Match
    • Employee Stock Purchase Plan

    Learn more about Revvity’s benefits by visiting our Bswift page. Log-In instructions are provided towards the bottom of the Bswift page.

    For benefit-eligible roles only. Part-time and temporary roles may not be eligible for all benefits listed. Please reach out to your recruiter for more information.

    Apply Now

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